
Abiomed (NASDAQ:
ABMD) has developed a portfolio of heart support and recovery products
and services which offer healthcare professionals an array of choices
across a broad clinical spectrum. From the catheterization lab to the
surgical suite, together with interventional cardiologists and surgeons,
Abiomed is dedicated to providing the most advanced medical technologies
to heart patients, with the ultimate goal of heart recovery and improved
quality of life.

Accumetrics,
Inc.
a point of care diagnostic company,
develops, manufactures, and markets the VerifyNow™ System, a comprehensive system for the
assessment of platelet function. Modulation of platelet function plays a
critical role in effectively treating cardiovascular, cerebrovascular,
and peripheral vascular disease. Accumetrics markets VerifyNow™ tests
for aspirin, Plavix® and GP IIb/IIIa inhibitors.

BioForm Medical, Inc.
is a medical device company introducing a family of proprietary, injectable
implant products used in minimally invasive soft tissue augmentation
procedures. The lead products, Coaptite® and Radiesse™, will be used
in the treatment of stress urinary incontinence, pediatric
vesicoureteral reflux, cosmetic tissue augmentation, and vocal fold insufficiency or
paralysis.

Clear Vascular, Inc was founded by Essex Woodlands Health
Ventures in 2005. The primary objective of the company is to develop
innovative cardiovascular products.

Echo Therapeutics (formerly
Sontra Medical, Inc.) is focused on transdermal continuous glucose
monitoring (tCGM) systems for people with diabetes and advanced topical
reformulations of FDA-approved specialty pharmaceuticals. Echo's
Symphony™
tCGM is a next generation, non-invasive (needle-free), wireless, tCGM
system in development for home use and hospital critical care
markets.

InSound Medical
is an early stage company founded in 1998 to develop
minimally invasive hearing products designed to overcome dissatisfaction
among current hearing aid wearers as well as barriers to use among
hearing impaired non-users. The Company will utilize ear-nose-throat (ENT)
physicians to market and install their devices.
ENT’s have heretofore been excluded from the $2 billion hearing
aid market.

LipoSonix
is a medical device company focused on the development of proprietary
technology for noninvasive cosmetic surgery applications. Current product development efforts
are targeted at the aesthetic body contouring market.

Medlogics is an early stage medical device company developing
a broad platform technology for innovative drug delivery. The initial
focus is product development of polymer-free stent drug delivery.

MicroMed Cardiovascular, Inc. (now E-Wilson, LLC)
has developed the DeBakey ventricular assist device (VAD) pioneered
by famed heart surgeon Dr. Michael E. DeBakey under a joint research and
development collaboration with NASA. The DeBakey VAD serves as a bridge
to heart transplant, a bridge to native heart recovery, and/or treatment
for congestive heart failure.

MicroPort
Medical (Shanghai) Co. Ltd. is an entrepreneurial, innovative company. Its aim is
to provide leading technologies and products for physicians, with
life-saving solutions and treatments for patients. In close cooperation
with recognized international physicians and scientists worldwide, the
company has developed a range of interventional vascular products that
meet the highest quality and clinical standards.

Nellix, Inc., is a
privately funded, medical device startup company located in Mountain
View, CA. Nellix is actively developing novel solutions to vascular
diseases affecting millions of patients world wide.

NeoVista, Inc. is developing an intraocular epiretinal radiation device
intended for the treatment of the wet form of Age-Related Macular
Degeneration (AMD).

Novacept
designs, develops, manufactures and markets innovative therapeutic
devices to improve the quality of women's healthcare in a cost-effective
manner. Novacept was sold to
Cytyc Corporation in March 2004.

Oraya Therapeutics, Inc. is a privately held company
developing medical devices.

Orthopedic Resources, Inc. (dba Bledsoe Brace
Systems)
is
a leader in the orthopedic bracing market. Founded in
1982, it was the first company to develop a post-operative knee brace,
and has continued to build on its 25-year reputation of quality clinical
products and design leadership. Bledsoe’s products are used both domestically and internationally by orthopedic surgeons, podiatrists, orthotists, and physical therapists to address musculoskeletal disorders
of their patients by supporting and protecting injured or weakened
joints.

Orthovita is a unique spine/orthopaedic surgical biomaterials company offering advanced bone regeneration and soft tissue healing technologies. Their experience lies in developing and distributing novel, high-tech, synthetic-based biomaterial products. Orthovita currently has four key commercial product platforms: Vitoss Bone Graft Substitute, Vitagel Surgical Hemostat, Cortoss Synthetic Cortical Bone, and Imbibe Delivery and Disposable Systems.

Proteus Biomedical
was founded in 2001 to apply its state-of-the-art
semiconductor technology to the treatment of cardiovascular disease. The company's clinical focus is on the management
of congestive heart failure (CHF), a debilitating condition resulting
from progressive weakening of the heart's pumping ability. Proteus
Biomedical is based in Silicon Valley, California. Its products are
currently under development.

ROX Medical
represents a mid-late stage medical device opportunity in the large,
growing, underserved market of late end state COPD (chronic obstructive
pulmonary disease) patients.

Sound ID's proprietary sound source signal
enhancement technology, deployable in a wide variety of products in the communication and entertainment
markets, provides personalization of sound to an
individual’s unique hearing profile, and dynamic optimization of sound
in response to noise in the listener’s environment.

Thermage
markets non-invasive skin tightening
devices for cosmetic indications. The system heats the deep skin
tissues, causing collagen shrinkage, while
cooling the skin surface. No
incisions are required and side effects associated with lasers are
avoided. The technology has multiple potential applications, including
treatments for facial skin tightening, acne and acne scarring, stretch
marks, breast lifting and fat dissipation. Several types of disposable
treatment tips are designed for various applications and anatomic sites.
Thermage has secured regulatory clearance for marketing the system.
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